NJACT: Not Just Another Cancer Thread
- Thread starter SeoReborn
- Start date
So sorry about your grandfather.
Your grandfather must have been really fit to experience very little side effects from the chemo. I am sure the fasting must have helped too.
Again from the same large review http://www.nutritionandmetabolism.com/content/pdf/1743-7075-8-75.pdf
In a nutshell, low carb ketogenic diet gets the same benefits as fasting. While you can only fast for a short period of time, a low carb ketogenic diet can be used indefinately.
Not been updating the thread for the past month because my Dad has been on and off his supplements. He is nescient to alternative treatments (and orthodox ones), and so his paranoia has got the better of him. As from last Thursday, he stopped his supplements, and yesterday have stopped the low carb ketogenic diet. So he is back to eating biscuits, bread and whatever he likes.
Today, he will go to see the oncologist from transferred hospital. Last week they took another CT scan. So between the 2 CT scans seperated by around 2 months, they hope to determine how aggressive the cancer is. In reality, I don't see this as a good measure for the future as he was on a ketogenic diet plus intermittent supplements for that time.
Another thing is that since his lung drainage 2 months ago, he has not required any drainage since. So whether its to do with the diet and supplements, maybe.
The oncologist last week also said they will do a lower dosage of chemotherapy for him compared to the plan of the previous oncologist, so as to 'lessen' the side effects.
As always, I will leave it to my Dad as to what he wants to do.
Today, he will go to see the oncologist from transferred hospital. Last week they took another CT scan. So between the 2 CT scans seperated by around 2 months, they hope to determine how aggressive the cancer is. In reality, I don't see this as a good measure for the future as he was on a ketogenic diet plus intermittent supplements for that time.
Another thing is that since his lung drainage 2 months ago, he has not required any drainage since. So whether its to do with the diet and supplements, maybe.
The oncologist last week also said they will do a lower dosage of chemotherapy for him compared to the plan of the previous oncologist, so as to 'lessen' the side effects.
As always, I will leave it to my Dad as to what he wants to do.
Are you dense?
An MRI scan costs something like $200-400 everywhere but in the extremely corrupt US health care system.
Stupid ass Americans accept everything people with a shirt tell them.
Could literally fly to Singapore on business class tickets for that scan and back again for the price of an American MRI.
Good luck OP. 83 is a decent age, though of course you want him to live to be at least 100, at least regardless of what happens, he will have had a long life.
I think there is a good amount of research out there for 'alternative' approaches, meaning mostly diets and also some supplements. There is also a lot of utter bs. You seem to be able to discern the good from the bad. Starving cancer through eliminating glucose and fasting seems to me, to make a lot of sense.
I don't want to give advice for or against, but it seems to me that invasive surgery, radiotherapy and chemotherapy is tough going for anyone, but particularly for older people with lessened immune systems.
I wish you and your dad the best and remember to enjoy the time together in any case.
I think there is a good amount of research out there for 'alternative' approaches, meaning mostly diets and also some supplements. There is also a lot of utter bs. You seem to be able to discern the good from the bad. Starving cancer through eliminating glucose and fasting seems to me, to make a lot of sense.
I don't want to give advice for or against, but it seems to me that invasive surgery, radiotherapy and chemotherapy is tough going for anyone, but particularly for older people with lessened immune systems.
I wish you and your dad the best and remember to enjoy the time together in any case.
Don't respond to this idiot.http://www.wickedfire.com/2211266-post2161.html
NOBODY uses MRI to image the lungs.
How are your dad's liver enzymes? Ubiquinol is excellent due to dad's age, but I would also take the redox (ubiquinone) in coconut oil. Melt 14 oz of coconut oil on the stove under low-heat and put it back in the bottle. Add 56oz of CoQ10 powder. 500mg/tsp, twice daily. It's freely converted (cell), even if he has liver-involvement.
IP6 is phenomenal.
You fucking worm. You can't image the lungs with an MRI. You really need to stfu.
http://www.wickedfire.com/2211221-post2145.html
OP, Warburg is a dead-end. You cannot eliminate glucose -> glycogen. It's manufactured endogenously even under strict keto diets. Two large studies have shown that tumor progression was unch between the high-carb and keto diets. A lot more has been discovered since Warburg's days. There is differentiation within a mass in which some cells exhibit Warburg and some do not. Like the blood alkalinity argument. You cannot alkalize blood, only piss. Just as an analogy to the Warburg supporters.
Some interesting info here: Blood Sugar is Stable
Some interesting info here: Blood Sugar is Stable
@poopie, will reply to you later about the coq10 and blood sugar stuff
CT SCAN result: No growth in tumor
I did not go to the oncologist with Dad today, it is what my sister just relayed to me.
The first oncologist said 2 months ago that his cancer is on the aggressive side and hence his life expectancy toward 6 months (which now should be 4 months as 2 months have passed). So the tumor having not grown is an unexpected result.
However as I said before, this will no longer be a good predictor of future growth since he has stopped his supplements and diet altogether.
CT SCAN result: No growth in tumor
I did not go to the oncologist with Dad today, it is what my sister just relayed to me.
The first oncologist said 2 months ago that his cancer is on the aggressive side and hence his life expectancy toward 6 months (which now should be 4 months as 2 months have passed). So the tumor having not grown is an unexpected result.
However as I said before, this will no longer be a good predictor of future growth since he has stopped his supplements and diet altogether.
Awesome news.
FWIW, there is no harm in going keto and high fat. I would do that if it were me, as it can't hurt. How about adding MCT oil when/if he goes back on the supps. Make sure dad is getting enough fiber. Costco's resveratrol is of the 50% (high emodin) variety and will keep things moving. Oh, you're in the UK? Anyway, any high-emodin resveratrol will work.
My background is in this field. I did doctoral research in oncology (P-gp inhibition with CCA using Dox in refractory MBC).
FWIW, there is no harm in going keto and high fat. I would do that if it were me, as it can't hurt. How about adding MCT oil when/if he goes back on the supps. Make sure dad is getting enough fiber. Costco's resveratrol is of the 50% (high emodin) variety and will keep things moving. Oh, you're in the UK? Anyway, any high-emodin resveratrol will work.
My background is in this field. I did doctoral research in oncology (P-gp inhibition with CCA using Dox in refractory MBC).
My Dad was on high dose Ubiquinol, 400mg. From my understanding ubiquinol is much more bioavailable than ubiquinone and thus would provide much higher COQ10 blood levels. Moreover, ubiquinone needs to be converted into the reduced form ubiquinol for is beneficial effects. Through senescence, we lose our capability for this conversion, hence its particularly useful for my dad in this form.
Has Your CoQ10 Become Obsolete? - Life Extension
Does the ubiquinone go through some changes when heated with coconut oil?
Since in the earlier posts, it has been claimed that my supplements is nothing more than a multivitamin, I said I would list each one and explain why I am including it, so I'll start with Ubiquinol.
Why Ubiquinol
Benefits of Ubiquinol on cancer: Coenzyme Q10 (PDQ®) - National Cancer Institute
Ubiquinol Cancer Related Studies
There are plenty of studies including humans and animals, but I will just list some human studies otherwise the list would be too long.
Study 1:
Progress on therapy of breast cancer with vitamin Q10 and the regre... - PubMed - NCBI
Study 2:
Partial and complete regression of breast cancer in patients in rel... - PubMed - NCBI
Study 3:
Anti-angiogenic potential of CoenzymeQ10, riboflavin and niacin in ... - PubMed - NCBI
Study 4:
http://www.ncbi.nlm.nih.gov/pubmed/16443053
Study/review:
http://www.ncbi.nlm.nih.gov/pubmed/8476426
So that is why I chose Ubiquinol and a dosage of 400mg. In addition, ubiquinol is good for protecting the liver from the apoptosis/necrosis of cancer cells.
It is. Did you do research into it during your doctorate? I'm in contact with the lead IP6 cancer researcher Dr Shamsuddin.
ubiquinol is great stuff, no doubt. Now, The studies are contrasting the plasma conc. of a ubiquinol suspension (gel cap containing soy oil) vs. ubiquinone capsules containing powder (no carrier). 'ol is more quickly absorbed during the passive transport phase (diffusion) due to it's being more hydrophilic. It will achieve a significant plasma conc. faster, for sure.
'ol is the reduced form. Many supps are converted through first-pass in the liver. Ubiquinone is freely converted in the cell to a eq. state in complex three of ETC/mitochondrial redox. Kaneka is largely responsible for funding research into 'ol use as a retail supplement. A conflict of interest, but I don't doubt the results.
'ol is very unstable and it degrades rapidly. Yes, it's more bioavailable, but IMO the cost benefit isn't there.
I owned a board in which we had another doc who was involved in the debate. He did 1g/day of ubiquinol daily for a week and then drew blood for analysis six hours after the last dose. He waited a month-off and then took 1g of the ubiquinone bound to coconut oil. Samples taken six hours after the last oral dose of ubiquinone. An HPLC test was performed on both samples.
The plasma concentration was virtually identical. They ran each test twice. Understand that ubiquinone bound to coconut oil is ideal. I wouldn't cook it, but no damage will be done. Melt the oil slowly on low heat -> back in jar -> add powder. Now Foods sells a 28g bottle of pure powder.
'ol is the reduced form. Many supps are converted through first-pass in the liver. Ubiquinone is freely converted in the cell to a eq. state in complex three of ETC/mitochondrial redox. Kaneka is largely responsible for funding research into 'ol use as a retail supplement. A conflict of interest, but I don't doubt the results.
'ol is very unstable and it degrades rapidly. Yes, it's more bioavailable, but IMO the cost benefit isn't there.
I owned a board in which we had another doc who was involved in the debate. He did 1g/day of ubiquinol daily for a week and then drew blood for analysis six hours after the last dose. He waited a month-off and then took 1g of the ubiquinone bound to coconut oil. Samples taken six hours after the last oral dose of ubiquinone. An HPLC test was performed on both samples.
The plasma concentration was virtually identical. They ran each test twice. Understand that ubiquinone bound to coconut oil is ideal. I wouldn't cook it, but no damage will be done. Melt the oil slowly on low heat -> back in jar -> add powder. Now Foods sells a 28g bottle of pure powder.
No, just that I believe that IP6 is basically a vaccine for breast cancer. My info is limited to use in women.
My mother in law had heart palpatations and other symptoms of heart failure. I gave her 300mg of ubiquinol (Kaneka, same as what my Dad was taking), and her heart palpitations went away and other symptoms went away immediately. Other people have said they used Ubiquinoine >1g for heart palpitations and there were no effect, untill they switched to 200-300mg ubiquinol. This is in line with the hypothesis that its the ubiquinol that provides the beneficial effect, and that ubiquinoine needs to be converted first. And for these effects, the ubiquinol would have to been stable enough to produce it.
Another reason I chose ubiquinol is that the human studies used ubiquinol for its positive anti-cancer results.
The results of that self experimentation is interesting. Would be good to test on subjects at different ages.
I'll check out the cost of the powder and see how it stacks up.