Fly of course! It would be more a hassle if you drive.
Drive = 10 hours of agony.
Fly = 1 hour of agony.
As has been illustrated in the thread, flying is a lot more time-consuming than that.
You have to pack everything down to the smallest possible size: extra time.
Don't forget most airlines make you pay extra for just about all your luggage now.
You have to figure out how to get to the airport. Are you going to park your car in a lot there? That's like $7-14 a day depending on how close you park.
You have to get to the airport early to park and take the shuttle. You have to check your baggage. You have to wait in line to go through security. You pray you don't get picked for extra attention.
You have to walk to your gate, which for me is usually the furthest terminal, because that's how I roll.
You wait to board. You board, waiting for everyone to figure out how to put their carry-ons in the overhead bins when they're full. You have to lock yourself down in the seat and hold it in case you need to use the bathroom until you're in flight and the seatbelt sign goes off.
You have to struggle with everything because plane seats are small and uncomfortable. Need to change your darling child? Good luck with that.
You finally land, after your neighbor passengers have complained about your crying baby because it's doing what babies do. You finally de-plane, ignoring the glares.
You pick up 127 pounds of luggage, and make your way to the car rental shuttle. You wait. The shuttle arrives and you get to the rental office and you fill out the paperwork and pay through the nose for a rental van, which of course doesn't have all the stuff in it that your van does. Did you bring your child car seat, or are you going to rent one? Either way: pain in the ass.
Finally, you're on the road to your destination. Figure 3 hours from start to finish to get on the plane, an hour or so in flight, and another hour and a half to de-plane and get a rental.
Do that in reverse for the return trip.
As opposed to car travel. Load up the car with everything you might ever need, not worrying about making it light, not having to decide which stuff is more important.
Stop to pee? Sure! Listen to music, stop for food, stop to change the kid, stop to look at a pretty sight, stop to walk around, stop to change drivers, turn up the music to drown out the screaming child, play a video for the child, feed the child... not having to worry about people bitching and glaring at you for propogating the species.
Yes, it's still faster to fly, but not 1 hour versus 10 hours. More like 5+ hours flying versus 10 hours driving, and flying, you end up with a strange car and half the stuff you really want to have with you.