FRO, will do.
HFT has a huge hit-rate, but a poor R/R. They earn like $0.03/share on average, but lose $0.10 when they're wrong. They had a road-show and then Knight blew-up. Virtu is the real-deal and I expect they will put a stupid multiple on them.
I trade a lot of listed (exchange) delta1 and don't have a problem with filling orders. Sure, you get pennied and it can be maddening. My firm did some internal study and figured it cause the equity side (distinct from FICC) some 400MM in fill quality.
It all started with Susquehanna back in the 90s. Any block interest would signal an algo to step in front of your order. It was rudimentary, but cost everyone a lot because of 1/8s. I was in index arb at the time and it was a big hit to trade baskets.
In futures you are essentially filling at mkt... and any fill to buy at the bid is only going to be filled if the mkt moves against you anyway. SO, any strat that works trading at mkt will work in futures. I would think that it may be an issue to trade intraday in SN (single-name) like GOOG, AAPL, but there is no stat-vol intraday. The haircut (4:1) intraday still won't earn you a living.
So... I think the impact is limited for the guy at home trading retail. There are structural issues (haircut and vola) which are a larger impediment. The good news is that mkts are generally tight in SN and options are listed weekly. I had a consulting client that left CSCO with a shit ton of stock and makes more trading equity vola from home. He has a colo server and all the bells and whistles as it gives him confidence to pull the trigger, but all that is needed is reasonably low-latency to your clearer (under 100ms), excel and a decent front end.