Move the taskbar to the top, Rocketdock for the dock, Rainmeter for the weather/clock/calendar/etc. Oh, and a different Windows theme (can't remember the name).
heres one of my workstations - yes its messy, yes I know where everything is. Every month I drag and drop all of the mess I've made onto the desktop and drop it into a cleanup folder... most important part is probably the chemdawg I'm about to smoke for 4:20 ... then I'll probably be in the bump when high thread =D