Just was listening to your interview on shoemoney from yesterday. I have been collecting e-mail for over a year now on a few of my sites. I only have about 15,000 leads and I haven't pushed any affiliate offers (lists are double-opt-in can spam compliant.)
On shoemoney you said you have affiliates with 20,000-30,000 user lists making $300-$400 a day -- is that consistantly $300 a day from a list that is growing by 100 or 200 opt ins a day? I always guessed that you needed 100,000+ to be making anything significant.